SCOPE Suppported Publications
“Experimental Treatments for Spinal Cord Injury: What you Should Know” Full Version
Vieri Failli, Naomi Kleitman, Daniel P Lammertse, Jane T.C. Hsieh, John D. Steeves, James W. Fawcett, Mark H. Tuszynski, Armin Curt, Michael G. Fehlings, James D. Guest, Andrew R. Blight
“Experimental Treatments for Spinal Cord Injury: What you Should Know”
Vieri Failli, Naomi Kleitman, Daniel P Lammertse, Jane T.C. Hsieh, John D. Steeves, James W. Fawcett, Mark H. Tuszynski, Armin Curt, Michael G. Fehlings, James D. Guest, Andrew R. Blight
Top Spinal Cord Inj Rehabil (2021) 27 (2): 50–74. 2021 May https://doi.org/10.46292/sci2702-50
“Adaptive Trial Designs for Spinal Cord Injury Clinical Trials Directed to the Central Nervous System”
Mulcahey MJ, Jones LAT, Rockhold F, Rupp R, Kramer JLK, Kirshblum S, Blight A, Lammertse D, Guest JD, Steeves JD
https://www.nature.com/articles/s41393-020-00547-8
Spinal Cord. 2020 Dec;58(12):1235-1248. PMID: 32939028.
2019 Best Review Paper for Spinal Cord
“Neurochemical biomarkers in spinal cord injury“
Kwon BK, Bloom O, Wanner IB, Curt A, Schwab JM, Fawcett J, Wang KK.
https://www.ncbi.nlm.nih.gov › pubmed
Spinal Cord. 2019 Oct. doi: 10.1038/s41393-019-0319-8. Epub 2019 Jul 4.
“Application of electrophysiological measures in spinal cord injury clinical trials: a narrative review.”
Hubli M, Kramer JLK, Jutzeler CR, Rosner, Furlan JC, Tansey KE, Schubert M.
https://www.ncbi.nlm.nih.gov › pubmed
Spinal Cord. 2019 Jul 23. doi: 10.1038/s41393-019-0331-z. [Epub ahead of print]
2019 Reader’s Choice Award for Best Review Paper in Spinal Cord
“Guidelines for the conduct of clinical trials in spinal cord injury: Neuroimaging biomarkers“
Seif M, Gandini Wheeler-Kingshott CA, Cohen-Adad J, Flanders AE, Freund P.
https://www.ncbi.nlm.nih.gov › pubmed
Spinal Cord Jul 2, 2019. https://doi.org/10.1038/s41393-019-0309-x
“The Challenge of Recruitment for Neurotherapeutic Clinical Trials in Spinal Cord Injury“
Blight AR, Hsieh J, Curt A, Fawcett JW, Guest JD, Kleitman N, Kurpad SN, Kwon BK, Lammertse DP, Weidner N, Steeves JD.
https://www.ncbi.nlm.nih.gov
Spinal Cord. 2019 May; 57(5):348-359. doi: 10.1038/s41393-019-0276-2. Epub 2019 Apr 8.
“The Spinal Cord Ability Ruler (SCAR) complements the Spinal Cord”
Steeves J, Curt A, Mehra M, Rupp R, Blight A, Maier D, Jones L, Lammertse D, Abel R, Kirshblum S, Weidner N
Spinal Cord. 2018. https://doi.org/10.1038/s41393-018-0064-4
“Spinal Cord Ability Ruler: An Interval Scale to Measure Volitional Performance after Spinal Cord Injury“
Reed R, Mehra M, Kirshblum S, Maier D, Lammertse D, Blight A, Rupp R, Jones L, Abel R, Weidner N, EMSCI Study Group, SCOPE, Curt A, Steeves J.
Spinal Cord. 2017. [Epubl ahead of print] PMID: 28322239 https://doi.org/10.1038/sc.2017.1
“Considerations and recommendations for selection and utilization of upper extremity clinical outcome assessments in human spinal cord injury trials”
Jones L, Bryden A, Wheeler T, Tansey K, Anderson K, Beattie M, Blight A, Curt A, Field-Fote E, Guest J, Hsieh J, Jakeman L, Kalsi-Ryan S, Krisa Laura, Lammertse D, Leiby B, Marino R, Schwab JM, Scivoletto G, Tulsky DS, Wirth E, Zariffa J, Kleitman N, Mulcahey MJ, Steeves J. 2017
Spinal Cord. 2017 Dec 28. doi: 10.1038/s41393-017-0015-5. [Epub ahead of print]
“Lower extremity outcome measures: considerations for clinical trials in spinal cord injury”
Bolliger M, Blight, AR, Field-Fote EC, Musselman K, Rossignol S, Barthélemy D, Bouyer L, Popovic MR, Schwab JM, Boninger ML, Tansey KE, Scivoletto G, Kleitman N, Jones LAT, Gagnon DH, Nadeau S, Haupt D, Awai L, Easthope CS, Zörner B, Rupp R, Lammertse D, Curt A, Steeves JD. 2018
Spinal Cord. 2018 July;56(7):628-642. doi: 10.1038/s41393-018-0097-8. Epub 2018 Apr 27. [Epub ahead of print]
“Challenges for defining minimal clinically important difference (MCID) after spinal cord injury.”
Wu X, Liu J, Tanadini LG, Lammertse DP, Blight AR, Kramer JL, Scivoletto G, Jones L, Kirshblum S, Abel R, Fawcett J, Field-Fote E, Guest J, Levinson B, Maier D, Tansey K, Weidner N, Tetzlaff WG, Hothorn T, Curt A, Steeves JD.
Spinal Cord. 2015 Feb;53(2):84-91. https://www.nature.com/articles/sc2014232 PMID: 25510192
“Toward Inclusive Trial Protocols in Heterogeneous Neurological Disorders: Prediction-Based Stratification of Participants With Incomplete Cervical Spinal Cord Injury.”
Tanadini LG, Hothorn T, Jones LA, Lammertse DP, Abel R, Maier D, Rupp R, Weidner N, Curt A, Steeves JD.
Neurorehabil Neural Repair. doi: 10.1177/1545968315570322. Epub 2015 Feb 2. PMID: 25644238
“Identifying Homogeneous Subgroups in Neurological Disorders: Unbiased Recursive Partitioning in Cervical Complete Spinal Cord Injury.”
Tanadini LG, Steeves JD, Hothorn T, Abel R, Maier D, Schubert M, Weidner N, Rupp R, Curt A.
Neurorehabil Neural Repair. 2014 Jan 28;28(6):507-515. PMID: 24477680
“Functional motor preservation below the level of injury in subjects with American Spinal Injury Association Impairment Scale grade A spinal cord injuries.”
Zariffa J, Curt A; EMSCI Study Group, Steeves JD.
Arch Phys Med Rehabil. 2012 May;93(5):905-7. Epub 2012 Feb 22. PMID: 22360976
“State of the Science in Spinal Cord Injury Rehabilitation 2011: informing a new research agenda.”
Heinemann AW, Steeves JD, Boninger M, Groah S, Sherwood AM.
Spinal Cord. 2012 May;50(5):390-7. doi: 10.1038/sc.2012.12. Epub 2012 Mar 20. PMID: 22430512
“Sacral sparing in SCI: beyond the S4-S5 and anorectal examination.”
Zariffa J, Kramer JL, Jones LA, Lammertse DP, Curt A; European Multicenter Study about Spinal Cord Injury Study Group, Steeves JD.
Spine J. 2012 May;12(5):389-400.e3. Epub 2012 May 8. PMID: 22572584
“Relationship Between Motor Recovery and Independence After Sensorimotor-Complete Cervical Spinal Cord Injury.”
Kramer JL, Lammertse DP, Schubert M, Curt A, Steeves JD.
Neurorehabil Neural Repair. 2012 May 30. [Epub ahead of print] PMID: 22647878
“Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury.”
Steeves JD, Kramer JK, Fawcett JW, Cragg J, Lammertse DP, Blight AR, Marino RJ, Ditunno JF Jr, Coleman WP, Geisler FH, Guest J, Jones L, Burns S, Schubert M, van Hedel HJ, Curt A; EMSCI Study Group.
Spinal Cord. 2011 Feb;49(2):257-65. Epub 2010 Aug 17. PMID: 20714334
“Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury.”
Zariffa J, Kramer JL, Fawcett JW, Lammertse DP, Blight AR, Guest J, Jones L, Burns S, Schubert M, Bolliger M, Curt A, Steeves JD.
Spinal Cord. 2011 Mar;49(3):463-71. Epub 2010 Oct 12.
PMID: 20938451
“Outcome measures in spinal cord injury: recent assessments and recommendations for future directions.”
Alexander MS, Anderson KD, Biering-Sorensen F, Blight AR, Brannon R, Bryce TN, Creasey G, Catz A, Curt A, Donovan W, Ditunno J, Ellaway P, Finnerup NB, Graves DE, Haynes BA, Heinemann AW, Jackson AB, Johnston MV, Kalpakjian CZ, Kleitman N, Krassioukov A, Krogh K, Lammertse D, Magasi S, Mulcahey MJ, Schurch B, Sherwood A, Steeves JD, Stiens S, Tulsky DS, van Hedel HJ, Whiteneck G.
Spinal Cord. 2009 Aug;47(8):582-91. Epub 2009 Apr 21. Review. PMID: 19381157
“Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials.”
Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, Bartlett PF, Blight AR, Dietz V, Ditunno J, Dobkin BH, Havton LA, Ellaway PH, Fehlings MG, Privat A, Grossman R, Guest JD, Kleitman N, Nakamura M, Gaviria M, Short D.
Spinal Cord. 2007 Mar;45(3):190-205. Epub 2006 Dec 19. Review. PMID: 17179973
“Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures.”
Steeves JD, Lammertse D, Curt A, Fawcett JW, Tuszynski MH, Ditunno JF, Ellaway PH, Fehlings MG, Guest JD, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Short D, Nakamura M, Coleman WP, Gaviria M, Privat A; International Campaign for Cures of Spinal Cord Injury Paralysis.
Spinal Cord. 2007 Mar;45(3):206-21. Epub 2006 Dec 19. Review. PMID: 17179972
“Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial exclusion/inclusion criteria and ethics.”
Tuszynski MH, Steeves JD, Fawcett JW, Lammertse D, Kalichman M, Rask C, Curt A, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Privat A; International Campaign for Cures of Spinal Cord Injury Paralysis.
Spinal Cord. 2007 Mar;45(3):222-31. Epub 2006 Dec 19. Review. PMID: 17179971
“Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design.”
Lammertse D, Tuszynski MH, Steeves JD, Curt A, Fawcett JW, Rask C, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Blight AR, Dobkin BH, Grossman R, Katoh H, Privat A, Kalichman M; International Campaign for Cures of Spinal Cord Injury Paralysis.
Spinal Cord. 2007 Mar;45(3):232-42. Epub 2006 Dec 19. Review. PMID: 17179970