SCOPE Supported Publications
Exploring the Landscape of Biomarkers in Spinal Cord Injury
Scheuren PS, Kondiles BR, Filous AR, Bloom OE, Chow DS, Field-Fote EC, Freund P, Guest JD, Kwon BK, Kyritsis N, Leptak C, Perez MA, Szapacs M, West CR, Tansey K, Hsieh JTC, Jones L.
Top Spinal Cord Inj Rehabil. 2025 Spring;31(2):1-12. doi: 10.46292/sci24-00076
Lessons Learned and Recommendations from a SCOPE Spinal Cord Injury Neurorestorative Clinical Trials Update
Kondiles BR, Rana S, Weiner D, Blesch A, St John J, Haag-Molkenteller C, Freund P, Guest J, Mikol DD, Harkema S, Trumbower RD, Fehlings MG, Weidner N, Hogge GS, Field-Fote EC, Baptista MAS, Curt A, Hsieh J, Jones L.
Neurotrauma Rep. 2025 Mar 5;6(1):210-231. doi: 10.1089/neur.2024.0163
Embracing The Voices of Persons Affected by Spinal Cord Injury: A Roadmap to Addressing Unmet Needs in Spinal Cord Injury Care Through Patient-Focused Drug Development (White Paper)
Baptista M, Culley B, Kirshblum S, Lauw M, Moynahan M, Mulcahey MJ, Munro B, Jones L, Hsieh J.
Spinal Cord Outcomes Partership Endeavor (SCOPE), 2025. https://scope-sci.org/wp-content/uploads/2025/09/Final-SCI-PI-PFDD-White-Paper.pdf
Data Safety Monitoring Boards: Overview of Structure and Role in Spinal Cord Injury Studies
Blight AR, Guest JD, Hamer J, Hsieh JTC, Jones L, Magnuson DSK, Pfleeger K.
Top Spinal Cord Inj Rehabil. 2024 Summer;30(3):67-75. doi: 10.46292/sci23-00084
Experimental Treatments for Spinal Cord Injury: What you Should Know – Full Version
Failli V, Kleitman N, Lammertse DP, Hsieh JTC, Steeves JD, Fawcett JW, Tuszynski MH, Curt A, Fehlings MG, Guest JD, Blight AR.
Spinal Cord Outcomes Partership Endeavor (SCOPE), 2021. https://scope-sci.org/wp-content/uploads/2021/10/Experimental-Treatments-Full-PWP.pdf
Experimental Treatments for Spinal Cord Injury: What you Should Know
Failli V, Kleitman N, Lammertse DP, Hsieh JTC, Steeves JD, Fawcett JW, Tuszynski MH, Curt A, Fehlings MG, Guest JD, Blight AR.
Top Spinal Cord Inj Rehabil (2021) Spring 27 (2): 50–74. doi: 10.46292/sci2702-50
Adaptive Trial Designs for Spinal Cord Injury Clinical Trials Directed to the Central Nervous System
Mulcahey MJ, Jones LAT, Rockhold F, Rupp R, Kramer JLK, Kirshblum S, Blight A, Lammertse D, Guest JD, Steeves JD
Spinal Cord. 2020 Dec;58(12):1235-1248 doi: 10.1038/s41393-020-00547-8
2019 Best Review Paper for Spinal Cord
Neurochemical biomarkers in spinal cord injury
Kwon BK, Bloom O, Wanner IB, Curt A, Schwab JM, Fawcett J, Wang KK.
Spinal Cord. 2019 Oct.57(10) doi: 10.1038/s41393-019-0319-8
Application of electrophysiological measures in spinal cord injury clinical trials: a narrative review
Hubli M, Kramer JLK, Jutzeler CR, Rosner J., Furlan JC, Tansey KE, Schubert M.
Spinal Cord. 2019 Nov;57(11):909-923 doi: 10.1038/s41393-019-0331-z
2019 Reader’s Choice Award for Best Review Paper in Spinal Cord
Guidelines for the Conduct of Clinical Trials in Spinal Cord Injury: Neuroimaging Biomarkers
Seif M, Gandini Wheeler-Kingshott CA, Cohen-Adad J, Flanders AE, Freund P.
Spinal Cord. 2019 Sep;57(9):717-728. doi: 10.1038/s41393-019-0309-x
The Challenge of Recruitment for Neurotherapeutic Clinical Trials in Spinal Cord Injury
Blight AR, Hsieh J, Curt A, Fawcett JW, Guest JD, Kleitman N, Kurpad SN, Kwon BK, Lammertse DP, Weidner N, Steeves JD.
Spinal Cord. 2019 May; 57(5):348-359. doi: 10.1038/s41393-019-0276-2
The Spinal Cord Ability Ruler (SCAR) complements the Spinal Cord Independence Measure (SCIM)
Steeves J, Curt A, Mehra M, Rupp R, Blight A, Maier D, Jones L, Lammertse D, Abel R, Kirshblum S, Weidner N
Spinal Cord. 2018 May;56(5):525-526. doi: 10.1038/s41393-018-0064-4
Spinal Cord Ability Ruler: An Interval Scale to Measure Volitional Performance after Spinal Cord Injury
Reed R, Mehra M, Kirshblum S, Maier D, Lammertse D, Blight A, Rupp R, Jones L, Abel R, Weidner N, EMSCI Study Group, SCOPE, Curt A, Steeves J.
Spinal Cord. 2017 Aug;55(8):730-738. doi: 10.1038/sc.2017.1
Considerations and Recommendations for Selection and Utilization of Upper Extremity Clinical Outcome Assessments in Human Spinal Cord Injury Trials
Jones LAT, Bryden A, Wheeler TL, Tansey KE, Anderson KD, Beattie MS, Blight A, Curt A, Field-Fote E, Guest JD, Hseih J, Jakeman LB, Kalsi-Ryan S, Krisa L, Lammertse DP, Leiby B, Marino R, Schwab JM, Scivoletto G, Tulsky DS, Wirth E, Zariffa J, Kleitman N, Mulcahey MJ, Steeves JD.
Spinal Cord. 2018 May;56(5):414-425. doi: 10.1038/s41393-017-0015-5
Lower Extremity Outcome Measures: Considerations for Clinical Trials in Spinal Cord Injury
Bolliger M, Blight AR, Field-Fote EC, Musselman K, Rossignol S, Barthélemy D, Bouyer L, Popovic MR, Schwab JM, Boninger ML, Tansey KE, Scivoletto G, Kleitman N, Jones LAT, Gagnon DH, Nadeau S, Haupt D, Awai L, Easthope CS, Zörner B, Rupp R, Lammertse D, Curt A, Steeves J.
Spinal Cord. 2018 July;56(7):628-642. doi: 10.1038/s41393-018-0097-8
Challenges for defining minimal clinically important difference (MCID) after spinal cord injury
Wu X, Liu J, Tanadini LG, Lammertse DP, Blight AR, Kramer JL, Scivoletto G, Jones L, Kirshblum S, Abel R, Fawcett J, Field-Fote E, Guest J, Levinson B, Maier D, Tansey K, Weidner N, Tetzlaff WG, Hothorn T, Curt A, Steeves JD.
Spinal Cord. 2015 Feb;53(2):84-91.doi: 10.1038/sc.2014.232
Toward Inclusive Trial Protocols in Heterogeneous Neurological Disorders: Prediction-Based Stratification of Participants With Incomplete Cervical Spinal Cord Injury
Tanadini LG, Hothorn T, Jones LAT, Lammertse DP, Abel R, Maier D, Rupp R, Weidner N, Curt A, Steeves JD.
Neurorehabil Neural Repair. 2015 Oct;29(9):867-77. doi:10.1177/1545968315570322
Identifying Homogeneous Subgroups in Neurological Disorders: Unbiased Recursive Partitioning in Cervical Complete Spinal Cord Injury
Tanadini LG, Steeves JD, Hothorn T, Abel R, Maier D, Schubert M, Weidner N, Rupp R, Curt A.
Neurorehabil Neural Repair. 2014 Jul;28(6):507-15. doi: 10.1177/1545968313520413
Functional Motor Preservation Below the Level of Injury in Subjects With American Spinal Injury Association Impairment Scale Grade A Spinal Cord Injuries
Zariffa J, Curt A; EMSCI Study Group, Steeves JD.
Arch Phys Med Rehabil. 2012 May;93(5):905-7. doi: 10.1016/j.apmr.2011.10.024
State of the Science in Spinal Cord Injury Rehabilitation 2011: informing a new research agenda
Heinemann AW, Steeves JD, Boninger M, Groah S, Sherwood AM.
Spinal Cord. 2012 May;50(5):390-7. doi: 10.1038/sc.2012.12
Sacral Sparing in SCI: Beyond the S4-S5 and Anorectal Examination
Zariffa J, Kramer JLK, Jones LAT, Lammertse DP, Curt A; European Multicenter Study about Spinal Cord Injury Study Group, Steeves JD.
Spine J. 2012 May;12(5):389-400.e3. doi: 10.1016/j.spinee.2012.03.028
Relationship Between Motor Recovery and Independence After Sensorimotor-Complete Cervical Spinal Cord Injury
Kramer JLK, Lammertse DP, Schubert M, Curt A, Steeves JD.
Neurorehabil Neural Repair. 2012 Nov-Dec;26(9):1064-71 doi:10.1177/1545968312447306
Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury
Steeves JD, Kramer JK, Fawcett JW, Cragg J, Lammertse DP, Blight AR, Marino RJ, Ditunno Jr JF, Coleman WP, Geisler FH, Guest J, Jones L, Burns S, Schubert M, van Hedel HJA, Curt A; EMSCI Study Group.
Spinal Cord. 2011 Feb;49(2):257-65. doi: 10.1038/sc.2010.99
Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury
Zariffa J, Kramer JL, Fawcett JW, Lammertse DP, Blight AR, Guest J, Jones L, Burns S, Schubert M, Bolliger M, Curt A, Steeves JD.
Spinal Cord. 2011 Mar;49(3):463-71. doi: 10.1038/sc.2010.140
Outcome Measures in Spinal Cord Injury: Recent Assessments and Recommendations for Future Directions
Alexander MS, Anderson KD, Biering-Sorensen F, Blight AR, Brannon R, Bryce TN, Creasey G, Catz A, Curt A, Donovan W, Ditunno J, Ellaway P, Finnerup NB, Graves DE, Haynes BA, Heinemann AW, Jackson AB, Johnston MV, Kalpakjian CZ, Kleitman N, Krassioukov A, Krogh K, Lammertse D, Magasi S, Mulcahey MJ, Schurch B, Sherwood A, Steeves JD, Stiens S, Tulsky DS, van Hedel HJ, Whiteneck G.
Spinal Cord. 2009 Aug;47(8):582-91. doi: 10.1038/sc.2009.18
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials
Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, Bartlett PF, Blight AR, Dietz V, Ditunno J, Dobkin BH, Havton LA, Ellaway PH, Fehlings MG, Privat A, Grossman R, Guest JD, Kleitman N, Nakamura M, Gaviria M, Short D.
Spinal Cord. 2007 Mar;45(3):190-205. doi.org/10.1038/sj.sc.3102007
Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures
Steeves JD, Lammertse D, Curt A, Fawcett JW, Tuszynski MH, Ditunno JF, Ellaway PH, Fehlings MG, Guest JD, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Short D, Nakamura M, Coleman WP, Gaviria M, Privat A; International Campaign for Cures of Spinal Cord Injury Paralysis.
Spinal Cord. 2007 Mar;45(3):206-21. doi.org/10.1038/sj.sc.3102008
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial exclusion/inclusion criteria and ethics
Tuszynski MH, Steeves JD, Fawcett JW, Lammertse D, Kalichman M, Rask C, Curt A, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Privat A; International Campaign for Cures of Spinal Cord Injury Paralysis.
Spinal Cord. 2007 Mar;45(3):222-31. doi: 10.1038/sj.sc.3102009
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design
Lammertse D, Tuszynski MH, Steeves JD, Curt A, Fawcett JW, Rask C, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Blight AR, Dobkin BH, Grossman R, Katoh H, Privat A, Kalichman M; International Campaign for Cures of Spinal Cord Injury Paralysis.
Spinal Cord. 2007 Mar;45(3):232-42. doi: 10.1038/sj.sc.3102010