Below is a Partner/Member suggested list of Peer-Reviewed Publications that align with the mission of SCOPE to "Enhance Spinal Cord Injury Research, including Development of Clinical Trial and Clinical Practice Protocols that will accurately and effectively validate Therapeutic Interventions in SCI.
Data Safety Monitoring Boards: Overview of Structure and Role in Spinal Cord Injury Studies
Andrew R. Blight, PhD; James D. Guest, MD; James Hamer; Jane T.C. Hsieh, MSc; Linda Jones, PT, PhD; David S.K. Magnuson, PhD; Kimberley Pfleeger, PhD
Top Spinal Cord Inj Rehabil (2024) https://doi.org/10.46292/sci23-00084
A Phase 1/2a Dose-Escalation Study of Oligodendrocyte Progenitor Cells in Individuals with Subacute Cervical Spinal Cord Injury
Richard G. Fessler MD, PhD, Reza Ehsanian MD, PhD, Charles Y. Liu PhD, MD, Gary K. Steinberg MD, PhD, Linda Jones PT, PhD, Jane S. Lebkowski PhD, Edward D. Wirth III MD, PhD, and Stephen L. McKenna MD
https://doi.org/10.3171/2022.5.SPINE22167
Cell-Based and Stem-Cell-Based Treatments for Spinal Cord Injury: Evidence from Clinical Trials
Carl M Zipser, Jacquelyn J Cragg, James D Guest, Michael G Fehlings, Catherine R Jutzeler, Aileen J Anderson, Armin Curt
Clinical Trial Designs for Neuromodulation in Chronic Spinal Cord Injury Using Epidural Stimulation
Maxwell Boakye, MD, MPH, MBA1,2 ; Beatrice Ugiliweneza, PhD, MSPH1,2,3; Fabian Madrigal, MD1; Samineh Mesbah, PhD2; Alexander Ovechkin, MD, PhD1,2; Claudia Angeli, PhD2,4,5; Ona Bloom, PhD6,7,8,9; Jill W. Wecht, EdD9,10; Bonnie Ditterline, PhD1,2; Noam Y. Harel, MD, PhD9,10; Steven Kirshblum, MD11,12; Gail Forrest, PhD12,13; Samuel Wu, PhD14; Susan Harkema, PhD1,2,5; James Guest, MD, PhD15
Development of a Systems Medicine Approach to Spinal Cord Injury
James D. Guest,1,* Margot Kelly-Hedrick,2 Theresa Williamson,3 Christine Park,2 Daniyal Mansoor Ali,4
Ahilan Sivaganesan,4 Chris J. Neal,5 Charles H. Tator,6 and Michael G. Fehlings6
History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004–2022
Charles H. Tator,1,* James D. Guest,2 Chris J. Neal,3 Susan P. Howley,4 Elizabeth G. Toups,5
James S. Harrop,6 Bizhan Aarabi,7 Christopher I. Shaffrey,8 and Michael G. Fehlings1
Importance of Prospective Registries and Clinical Research Networks in the Evolution of Spinal Cord Injury Care
Margot Kelly-Hedrik,1 Muhammad M. Abd-El-Barr,2 Bizhan Aarabi,3 Armin Curt,4 Susan P. Howley,5 James S. Harrop,6 Steven Kirshblum,7–9 Christopher J. Neal,10 Vanessa Noonan,11 Christine Park,1 Beatrice Ugiliweneza,12 Charles Tator,13 Elizabeth G. Toups,14 Michael G. Fehlings,13 Theresa Williamson,15 and James D. Guest16,*
Non-Invasive Spinal Cord Electrical Stimulation for Arm and Hand Function in Chronic Tetraplegia: A Safety and Efficacy Trial
Moritz C 1, Field-Fote EC 2, Tefertiller C 3, van Nes I 4, Trumbower R 5, Kalsi-Ryan S 6, Purcell M 7, Janssen TWJ 8, Krassioukov A 9, Morse LR 10, Zhao KD 11, Guest J 12, Marino RJ 13, Murray LM 14, 15, Wecht JM 15, Rieger M 16, Pradarelli J 16, Turner A 16, D’Amico J 16, Squair JW 17, Courtine G 17
Riluzole in Spinal Cord Injury Study (RISCIS)–Pharmacokinetic (PK) Sub-Study: An Analysis of Pharmacokinetics, Pharmacodynamics,and Impact on Axonal Degradation of Riluzole in Patients With Traumatic Cervical Spinal Cord Injury Enrolled in the RISCIS Phase III Randomized Controlled Trial
Diana Shu-Lian Chow,1,* Ashley Nguyen,1,2 Junghwa Park,1 Lei Wu,1,3 Elizabeth Gardiner Toups,4 James Shields Harrop,5 James David Guest,6 Karl Michael Schmitt,7 Bizhan Aarabi,8 Michael George Fehlings,9 Maxwell Boakye,10 and Robert Geroge Grossman11,**
Safety and Efficacy of Riluzole in Acute Spinal Cord Injury Study (RISCIS): A Multi-Center, Randomized, Placebo-Controlled, Double- Blinded Trial
Michael G. Fehlings,1,2,* Ali Moghaddamjou,1 James S. Harrop,3 Ralph Stanford,4 Jonathon Ball,5 Bizhan Aarabi,6 Brian J. C. Freeman,7 Paul M. Arnold,8 James D. Guest,9 Shekar N. Kurpad,10 James M. Schuster,11 Ahmad Nassr,12 Karl M. Schmitt,13 Jefferson R. Wilson,1 Darrel S. Brodke,14 Faiz U. Ahmad,15 Albert Yee,1 Wilson Z. Ray,16 Nathaniel P. Brooks,17 Jason Wilson,18 Diana S-L Chow,19 Elizabeth G. Toups,20 and Branko Kopjar21
Soluble Nogo-Receptor-Fc Decoy (AXER-204) in Patients with Chronic Cervical Spinal Cord Injury in the USA: a First-in-Human and Randomised Clinical Trial
George Maynard 1, Ramakrishnan Kannan 2, Jian Liu 2, Weiwei Wang 3, Tu Kiet T Lam 4, Xingxing Wang 2, Crista Adamson 1, Craig Hackett 1, Jan M Schwab 5, Charles Liu 6, Donald P Leslie 7, David Chen 8, Ralph Marino 9, Ross Zafonte 10, Adam Flanders 9, Gilbert Block 1, Erika Smith 1, Stephen M Strittmatter 11
Ten-year Safety of Pluripotent Stem Cell Transplantation in Acute Thoracic Spinal Cord Injury
Stephen L. McKenna MD, Reza Ehsanian MD, PhD, Charles Y. Liu PhD, MD, Gary K. Steinberg MD, PhD, Linda Jones PT, PhD, Jane S. Lebkowski PhD, Edward Wirth III MD, PhD, and Richard G. Fessler MD, PhD
The Importance of Prospective Registries and Clinical Research Networks in the Evolution of Spinal Cord Injury Care
Margot Kelly-Hedrik1, Muhammad M. Abd-El-Barr2, Bizhan Aarabi3, Armin Curt4, Susan P.
Howley5, James S. Harrop6 Steven Kirshblum7, Christopher J. Neal8, Vanessa Noonan9,
Christine Park1, Beatrice Ugiliweneza10, Charles Tator11, Elizabeth G. Toups12, Michael G. Fehling11, Theresa Williamson13, James D. Guest14