SCOPE Shorts are monthly presentations on relevant topics. Some shorts are publically available as clickable links below.
2024
- January 2024 – MS Outcomes Assessment Consortium Overview
Tim Coetzee, PhD Chief Advocacy, Services & Science Officer, National MS Society - February 2024 – NACTN: The North American Clinical Trials Network “RISCIS and Beyond”
James Guest MD, PhD, FAANS/University of Miami - March 2024 – PT-OT BDS Validity Study
Edelle Field-Fote, PT, PhD, FAPTA, FASIA, Shepherd Center - April 2024 – Standardized Testing Research InVivo Endeavor (STRIVE)
Marco Baptista, Christopher & Dana Reeve Foundation - June 2024 – DISCUS Trial: Duroplasty for the Injured Cervical Spinal Cord with Uncontrolled Swelling
Lukas Grassner, MD, PhD - July 2024 – Next Steps for an SCI Externally led PFDD meeting with the FDA
David Digby, Director Abbvie Global Commercial Development - August 2024 – SCITrialsFinder Interactive Platform
Paulina S. Scheuren, PhD - Outcomes of PLEX Engagement in Research Labs
Dr. Murray Blackmore, Nancy Nicholas
2023 - January 2023 – Lessons Learned Regarding Motor Training After SCI in Animal Models
Karim Fouad, PhD/University of Alberta - March 2023 – Non-replicative HSV-1 vectors use for long-term therapeutic approaches of secondary conditions following SCI
Mikael Constrastin/EG427 - May 2023 – Mitsubishi Trial updates
Konstantin Zubovskiy/Mitsubishi Tanabe Pharma - June 2023 – Adaptive Clinical Trials
Donald Berry/Berry Consultants - July 2023 – Healey ALS Platform Trial Presentation
Norbert Weidner, MD, James Barry - November 2023 – ISRT Precourse
- December 2023 – Central Cord Syndrome
Einat Haber, MD
2022
- January 2022 – Regulatory and Reimbursement Overview for Medical Devices
Megan Moynihan, PhD/Case Western Reserve University - February 2022 – Navigating the Complexities of Cell Replacement Therapy Development
Francois Binette, PhD/Lineage Cell Therapeutics - March 2022 – The Role of Data Science in Spinal Cord Injury Research
Catherine Jutzeler, Prof. Dr./ETH Zurich - May 2022 – Insights From Studies of NVG-291 in Animal Models of Peripheral Nerve Injury, Demyelination, and Ischemic Stroke That May be Relevant to Repair in SCI
Marc DePaul, PhD/NervGen Pharma Corp. - June 2022 – FDA Externally led Patient Focused Drug Development
Presented by Abbvie, Lineage, Jane Hsieh, Linda Jones - July 2022 – Making SCI trials more efficient with Neuroimaging Biomarkers
- November 2022 – Spinal Electrical Stimulation
Jim Guest, MD, PhD/University of Miami - November 2022 Learnings from Transcutaneous Stimulation
Edelle-Field-Fote/ Shepherd Center - December 2022 – The North American Spinal Cord Injury Consortium
Jennifer French/The North American Spinal Cord Injury Consortium
2021
- January 2021 – ASIA Outcomes Training
Mary Schmidt Read, PT, DPT, MS/Magee Rehabilitation - February 2021 – Electrophysiology in SCI
Armin Curt, Prof., Dr./University of Zurich
Jim Guest, MD, PhD/University of Miami - March 2021 – The International Spinal Cord Injury Physicial Therapy – Occupational Therapy Basic Data Set: Rationale, Evidence, and Validation
Edelle Field-Fote, PT, PhD/Shepherd Center - April 2021 – Biomarkers and the International Spinal Cord Injury Biobank (ISCIB)
Brian Kwon, MD, PhD/University of British Columbia - May 2021 – MRI Features of Spinal Cord Injury
Adam Flanders, MD/Thomas Jefferson University - June 2021 – SMART-IRB.org
Nichelle Cobb, PhD/SMART IRB
Ann Franklin, MSPH/SMART IRB ambassador - July 2021 – Spinal Cord Ability Ruler (SCAR) and Unbiased Recursive Partitioning (URP)
Marc Bolliger, PhD/University of Zurich - September 2021 – Digital Functional Assessment
Jose Zariffa/University of Toronto - October 2021 – Preclinical Data Informing Clinical Study Design
Kim Pfleeger, PhD/Abbvie Inc. - November 2021 – Data Sharing in SCI Research (ODC-SCI)
Karim Fouad, PhD/University of Alberta - December 2021 – Rasch Analysis FIM SCIM
Linda Jones, PT, PhD, Research Consultant/Thomas Jefferson University
2020
- September 2020 – Spinal Cord Injury Movement-Index
SCI-MI/MJ Mulcahey, PhD, OTR/L/Thomas Jefferson University - November 2020 – A Rodent-Human Sensorimotor Outcomes Matrix: Overlap and Gaps
David Magnuson, PhD/University of Kentucky - December 2020 – Combinatorial Approaches
Frank Bradke, PhD/Ludwig-Maximilians-Universität
SCOPE PLANNING COMMITTEE MEMBERS REPRESENT RESEARCH AND CLINICAL PRACTICE WITHIN UNIVERSITIES, HOSPITALS, CORPORATIONS, FOUNDATIONS, AND FEDERAL AGENCIES.
The Planning Committee of the Spinal Cord Outcomes Partnership Endeavor (SCOPE) is a group of experienced individuals, representing a variety of constituencies within spinal cord medicine.
SCOPE leaders:
Jane Hsieh, MSc, Co-Chair
Wings for Life
After receiving graduate neurophysiology training at McGill University, Jane has spent more than 30 years in spinal cord injury (SCI) research. Throughout her career, Jane has been involved with SCI research in academia, industry, non-profit organizations and in my own consulting business. Currently, Jane’s main focus is acting as the Executive Director of the Accelerated Translational Program of Wings for Life. Managing this portfolio requires up to date knowledge of SCI clinical trials from both scientific and operational perspectives. Overseeing two large multi-centre drug trials in chronic SCI and many smaller complex multi-centre trials in acute, chronic, drug, device, and biologic therapeutics has afforded Jane extensive experience in all aspects and types of clinical trials.
Linda Jones, PT, PhD, Co-Chair
University of Colorado
With more than 20 years of experience, Linda has applied her clinical expertise, serving as a consultant and staff member in a number of pharmaceutical, biotechnology, exoskeleton and healthcare settings. She worked at Geron Corporation from 2006-2011, preparing and managing the first clinical trial in the United States utilizing cells derived from human embryonic stem cells, in a Phase I study in patients with neurologically complete, sub-acute spinal cord injury. Prior to this, she worked with Proneuron Biotechnologies, the sponsor of the first Phase 1 cell-based study (autologous macrophage injection) in spinal cord injury, and subsequently managed the Phase II trial. Linda also worked at Denver Health Medical Center for 12 years, with a focus on physical therapy interventions in the intensive care unit. Linda has also participated in publications on updates to and challenging cases based on the International Standards for the Neurological Classification of Spinal Cord Injury.
SCOPE Members:
Linda Bambrick, PhD
National Institute of Neurological Disorders and Stroke (NINDS)
Andrew R. Blight, PhD
Acorda Therapeutics, Inc.
Philippe Chambon MD, PhD
EG427
Mikael Contrastin
EG427
Gregoire Courtine, PhD
Onward
Brian Culley
Lineage
Armin Curt, MD, FRCPC
Spinal Cord Injury Center | University of Zurich
Jessica D’Amico, PhD
Onward
Marc DePaul, PhD
NervGen Pharma
Adele Doperalski, PhD
NINDS
Eberhardt Elizabeth
NervGen Pharma
Vieri Faili, PhD
Wings for Life
Adam Ferguson, PhD
University of California, San Francisco
Edelle Field-Fote, PT, PhD, FAPTA
Shepherd Center, Atlanta
Dan Graves, PhD
Thomas Jefferson Hospital
James Guest, MD, PhD, FACS
The Miami Project to Cure Paralysis | University of Miami Miller School of Medicine
Cornelia Haag-Molkenteller, MD, PhD
CMO, EG47
James Hamer, BA
DP Clinical
Ioana Hone
Lineage
Catherine Jutzeler, Dr
ETH Zürich
Genki Kaneko
Mitsubishi Tanabe Pharma
Steven Kirshblum, MD
Kessler Institute for Rehabilitation
Naomi Kleitman, PhD
Craig H. Neilsen Foundation
John Kramer, PhD
ICORD
Audrey Kusiak, PhD
Department of Veterans Affairs Office of Research and Development
Daniel P. Lammerstse, MD
Craig Hospital
Dave Marver
Onward
Verena May, PhD
Wings for Life
Dan Mikol, MD, PhD
NervGen Pharma
Mary Jane Mulcahey, PhD, OTR/L
Jefferson School of Health Professions | Thomas Jefferson University
Kent New, MD, PhD
Ascension St. Vincent’s Neurosurgery
Nancy Nicholas
SCI Community Liaison
Kim Pfleeger
AbbVie
Devinder Poonian
DP Clinical
Erika Ross
Onward
John Steeves, PhD
University of British Columbia and Vancouver Coastal Health | Vancouver General Hospital
Keith Tansey, MD, PhD
University of Mississippi Medical Center | Spinal Cord Injury Clinic at the Jackson VA Medical Center
Tracey Wheeler, PhD
Craig Neilsen Foundation
Konstantin Zubovskiy
Mitsubishi Tanabe Pharma